Measurements of MP and PPT were obtained at three time points: baseline, at the end of treatment with low-level laser and 30 days after (follow-up). VAS was measured at the same times as above and weekly throughout the laser therapy. The Friedman test was used at a significance level of 5 % for data analysis. The study was approved by the Ethics Committee of the Federal University of Sergipe (CAAE: 0025.0.107.000-10). A reduction

in the GMD of crushed particles (p < 0.01) and an increase in PPT (p < 0.05) were seen only in the laser group when comparing the baseline and end-of-treatment values. Both groups showed a decrease in SNS-032 chemical structure pain intensity at the end of treatment. LLLT promoted an improvement in MP and PPT of the masticatory muscles.”
“Purpose of reviewAllergic reactions to stinging insects may be unexpected, frightening, and severe. A clear understanding of recent advances in the field facilitates appropriate care of children who experience severe reactions to hymenoptera stings.

Recent findingsRecent investigations have underscored the importance of appropriate patient selection for potentially life-saving venom immunotherapy. Venom immunotherapy is effective in preventing future anaphylaxis from hymenoptera stings. Immunotherapy is indicated for patients with a history of anaphylaxis.

Children who develop large local swelling or strictly cutaneous systemic reactions generally do not require immunotherapy. Component resolved diagnostic testing has been investigated to clarify the possibility of multiple venom allergies in patients with sensitization to multiple venoms.

SummaryRapid AR-13324 recognition and treatment of anaphylaxis are critical. Subsequent education about avoiding future stings and attention to emergency preparedness with appropriate prescription of self-injectable epinephrine is important. Referral of patients Selleckchem S3I-201 who have experienced venom-associated anaphylaxis for possible venom immunotherapy can prevent future severe episodes

of anaphylaxis resulting from stings.”
“The aim of this randomized, parallel, controlled clinical trial was to examine the clinical and biochemical efficacy of diode laser as an adjunct to scaling and root planing (SRP). Thirty chronic periodontitis patients were randomly assigned into two groups to receive SRP alone (control) or SRP followed by diode laser (test). Plaque index, gingival index, bleeding on probing, probing depth, and clinical attachment level were measured at baseline and at 1, 3, and 6 months after treatment. The gingival crevicular fluid levels of interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), interleukin-8 (IL-8), matrix metalloproteinase-1 (MMP-1), matrix metalloproteinase-8 (MMP-8) and tissue inhibitor matrix metalloproteinase-1 (TIMP-1) were analyzed by enzyme-linked immunosorbent assay. Test group showed significantly a better outcome compared to the control group in full-mouth clinical parameters.

2%) had experienced a major vascular event: 4 coronary artery disease; 4 cerebral non-fatal ischemic stroke; 2 cardiovascular + cerebrovascular event (p = 0.012). A prolonged antiplatelet treatment, prior to the major vascular event, was found in 5/45 cases (11.1%) vs 23/145 (15.9%) controls (p = 0.63). In contrast, a long-lasting administration of anti-hypertensive drugs, to achieve a control of blood pressure, was found in 83.4% of controls Selleck MLN2238 and only in 46.7% of cases (p < 0.0001). In conclusion, in a 8-yr follow-up, coronary artery disease and/or non-fatal ischemic stroke were more common in subjects with a history of RVO than in a large setting of subjects comparable for cardiovascular

risk factors. These data also argue for RVO as a vascular disease in which aggressive anti-hypertensive therapy to prevent stroke and/or myocardial infarction is needed. (C) 2010

Elsevier B. V. All rights reserved.”
“We analyze a microscopically based rate equation model for quantum dot lasers. The model separately treats the dynamics of electrons and holes, and the carrier-carrier scattering selleck chemicals llc rates depend nonlinearly on the wetting layer carrier densities. Our objective is to determine analytical expressions for the relaxation oscillation frequency and damping rate. To this end, we consider the Class B limit of the five rate equations and apply asymptotic techniques. We consider two cases corresponding to either equivalent or drastically different decay rates for the electrons and holes. We show how they contribute to increase the relaxation oscillation damping rate compared to the damping rate of the conventional laser and that there exist optimal conditions on the control parameters in order to observe maximum damping. (C) 2011 American Institute of Physics. [doi:10.1063/1.3587244]“
“Background Primary small cell carcinoma of the endometrium is very rare, and there have

been no reports on KIT and PDGFRA in endometrial small cell carcinoma.

Case report An 87-year-old woman was admitted to our hospital because of genital bleeding. Endometrial cytology and biopsy revealed small cell carcinoma. Scrutiny of the body showed stage Ill endometrial carcinoma with metastases. An immunohistochemical study of the biopsy specimens revealed positive reactions for synaptophysin, CD56, KIT, and this website PDGFRA, and negative reactions for cytokeratins, neuron-specific enolase, and chromogranin. A molecular genetic analysis using PCR-direct sequencing identified no mutations of KIT (exons 9, 11, 13, and 17) and PDGFRA (exons 12 and 18) genes. The patient received chemotherapy and radiation, but showed a downhill course, and died of carcinomatosis 6 months after the initial presentation.

Conclusion The present case is the first reported case of primary small cell carcinoma of the endometrium with an examination of KIT and PDGFRA expressions and KIT and PDFGRA gene mutations.

Similar to Siberian apricot, Manchurian apricot oil has low acid value, indicating that the two oils enabled direct base-catalyzed transesterified for biodiesel production without acid pretreatment. The fatty acid compositions of Manchurian apricot and Siberian apricot oils determined results showed a high percentage of monounsaturated fatty

acids (69.15% and 67.78%, respectively). Other than cetane number and oxidation stability, the properties of biodiesel made from the two oils conformed to EN 14214-08, ASTM D6751-10 and GB/T 20828-07 standards. In general, Manchurian apricot represents a potentially useful biodiesel feedstock. (C) 2013 Elsevier B.V. All rights reserved.”
“Objective: The purpose of the present study was to investigate the expression of the alpha 2-integrin subunit and heat shock protein 47 (Hsp47) in two families with isolated gingival Vistusertib mouse fibromatosis (GF) form and one family with GF associated with dental abnormalities and normal gingiva (NG).

Study Design: Immunohistochemistry was performed with antibodies against alpha 2-integrin and Hsp47 in specimens ARN-509 in vivo from two unrelated families with hereditary gingival fibromatosis (Families

1 and 2) and from one family with a gingival fibromatosis-associated dental abnormality (Family 3); NG samples were used for comparison. The results were analysed statistically.

Results: Immunoreactivity for alpha 2-integrin and Hsp47 was observed in the nucleus of epithelial cells of both the basal and suprabasal layer and a more discreet signal was noted in connective tissue in all study samples. Hsp47 showed higher immunoreactivity in Family 2 compared with the other families (p <= 0.05). Despite the markup alpha 2-integrin was higher in Family 3 there was no statistically significant difference between

the families studied (p >= 0.05).

Conclusions: selleck compound Our results confirmed the heterogeneity of GF, such that similar patterns of expression of the condition may show differences in the expression of proteins such as Hsp47. Although no difference in alpha 2-integrin expression was observed between GF and NG groups, future studies are necessary to determine the exact role of this protein in the various forms of GF and whether it contributes to GF pathogenesis.”
“Objective: To examine different aggrecanase generated fragments in synovial fluid (SF) from patients with acute and chronic knee injuries and from knee healthy subjects.

Methods: We prepared SF-D1 samples from acute (n = 35) and chronic (n = 35) knee injury patients and knee healthy subjects (n = 10). Aggrecan fragments were analyzed in the SF-D1 samples by quantitative (Cl, ARCS, KEEE and G3 antibodies) and non-quantitative (GRGT and AGEG antibodies) Western blot.

Results: ARGS-SELE, ARGS-chondroitin sulfate (CS)1, GRGT-, GLGS- and AGEG-G3 fragments were the main ARCS and G3 fragments in injured and reference samples.

Furthermore,

recent evidence Metabolism inhibitor indicates that aryl-hydrocarbon interacting protein gene mutations occur in > 10% of patients with sporadic macroadenomas that occur before 30 years of age, and in > 20% of children with macroadenomas. Genetic screening for aryl-hydrocarbon interacting protein gene mutations is warranted in selected high-risk patients who may benefit from early recognition and follow-up.”
“Objective. Herpetic gingivostomatitis (HGS) is a prevalent oral condition of viral origin. Some patients with HGS visit emergency departments for treatment. This study is aimed at determining the nationwide estimates of hospitalizations due to HGS in the United States.

Study Design. The Nationwide Inpatient Sample of the Agency for Healthcare Research and Quality was used for the years 2004 to 2010. Hospital admissions with a primary diagnosis of HGS were identified using International Classification of Diseases (ICD)-9-CM code 054.2.

Results. During the study period, a total of 12 536 hospitalizations were attributed to HGS, and the number of hospitalizations per year (mean, 1791) remained

fairly constant during the years examined. The median age was 3.2 years. The mean age (15.6 years for the overall period) ranged from a low of 15.2 in 2010 Sapanisertib to a high of 16.8 in 2007. The total charges that resulted from these hospitalizations were $229.4 million.

Conclusions. This study further confirms that substantial resources are spent in treating oral conditions in hospital settings.”
“Influenza A virus is an important respiratory pathogen that poses a considerable threat to public health each year during seasonal epidemics and even more so when a pandemic strain emerges. Understanding the mechanisms involved in controlling an influenza infection within a host is important and could result in new and effective treatment strategies. Kinetic models of influenza viral growth and decay can summarize data and evaluate the biological parameters governing interactions between the virus and the host. Here we discuss recent viral kinetic models for influenza. We show how these models

have been used to provide insight into influenza pathogenesis selleckchem and treatment, and we highlight the challenges of viral kinetic analysis, including accurate model formulation, estimation of important parameters, and the collection of detailed data sets that measure multiple variables simultaneously. (C) 2010 John Wiley & Sons, Inc. WIREs Syst Biol Med 2011 3 429-445 DOI: 10.1002/wsbm.129″
“Background We investigated the association between genetic variation in chromosomal region 20p13-p12 (ADAM33 and flanking genes ATRN, GFRA4, SIGLEC1 and HSPA12B) and asthma. Amongst asthmatics, we then investigated the association between genetic variants and asthma severity. We evaluated the effect of environmental tobacco smoke (ETS) exposure in the context of genetic variants.

Patients and Methods: Patients were included at 163 dermatological centers selleck compound if they either had been treated continuously with FAE for at least 24 months, or for 36 months with interruptions of no longer than 6 months. Data were reported from baseline, after 3,

6, 12, 24, and 36 or more months of therapy. Safety parameters were monitored and the severity of skin symptoms was assessed by “”Physician’s Global Assessment”" (PGA) and “”Psoriasis Area and Severity Index”" (PASI).

Results: 984 patients were included with a mean duration of 44 months of continuous treatment. The percentage of patients documented as markedly improved or clear was 67 % after six months, selleck kinase inhibitor 78 % after 24 months, and 82 % after 36 months of therapy. Improvement was similar in patients with moderate and severe disease. Changes of laboratory parameters were usually insignificant and did not require a modification of FAE treatment in more than 90 % of the cases.

Conclusions: In the long-term treatment of patients with moderate and severe psoriasis FAE show a good and sustained

clinical efficacy combined with a favorable safety profile.”
“Objectives: To report 4 cases of cocaine-related purpura and to review previously reported cases of levamisole, levamisole-contaminated cocaine, and cocaine-induced vasculopathy.

Methods: We describe 4 patients suspected of vasculopathy associated with levamisole-tainted cocaine use. A retrospective review of the literature was performed using the PubMed, PubJet, MD consult, and Cochrane review databases.

Results: Four cases (2 females and 2 males), 46 to 55 years of age, presented with cocaine-related purpura, mainly affecting the ears, neutropenia, and autoantibodies. Skin biopsies revealed a mixed pattern of leukocytoclastic vasculitis and microvascular thrombosis in 2 cases, and pure thrombosis in the third case. The mixed vasculopathic pattern in association with neutropenia, both known adverse effects of levamisole, and levamisole positivity in 2 cases point to this compound as the true

etiologic agent in our patients. Eleven cases of levamisole-contaminated cocaine-induced vasculopathy have Nepicastat price been described in the English literature. Among these, 10 were females. Age range was 22 to 57 years. Urine levamisole positivity was tested and confirmed in 3 of the 11 cases. The clinical characteristics, laboratory features, histology, treatment, and recovery rates were compared for the published cases of levamisole, levamisole-contaminated cocaine, and cocaine-induced vasculopathy.

Conclusions: Adulterated cocaine abuse is an increasingly recognized phenomenon in North America. Levamisole is among the many contaminants that have been detected in seized cocaine throughout North America and Europe.

Inflammation and inflammatory cytokines in synovial fluid (SF) contribute to OA progression. Intra-articular (IA) injections of multipotent mesenchymal stromal cells (MSCs) are employed to treat OA in both humans and animals. MSCs secrete paracrine pro-inflammatory and anabolic signaling molecules that promote tissue repair. The objective of this study was to investigate the effects of OASF on the gene expression of paracrine signaling molecules by MSCs.

Methods: The effects of Lipopolysaccharide

selleck kinase inhibitor (LPS) and interleukin (IL)-1 beta as well as both normal (N) and osteoarthritis (OA) SF stimulations on the expression of paracrine pro-inflammatory (tumor necrosis factor (TNF)-alpha, IL-1 beta, IL-8), modulatory (IL-6) and anabolic (vascular endothelial growth factor (VEGF), transforming growth factor (TGF)-beta 1 and insulin-like growth factor (IGF)-1) signaling molecules by equine bone marrow multipotent mesenchymal stromal cells (eBM-MSCs) was investigated employing reverse transcriptase-polymerase chain reaction

(RT-PCR).

Results: In contrast with NSF, OASF significantly up-regulated the expression click here of VEGF in eBM-MSCs. Both NSF and OASF significantly down-regulated the expression of IL-1 beta. LPS and IL-1 beta significantly increased the expression of pro-inflammatory cytokines (TNF-alpha, IL-8 and IL-6; and IL-1 beta and IL-8 respectively).

Discussion: We conclude that the transcription of paracrine signaling molecules in eBM-MSCs is modulated by SF. Furthermore, OA alters the properties of SF and the response of eBM-MSCs.

Finally, the effects of LPS or IL-1 beta stimulation are distinct to that observed following stimulations with OASF. (C) 2013 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.”
“SETTING: A national tuberculosis (TB) drug resistance survey in Tanzania.

OBJECTIVE : To compare the performance of the Genotype (R) MTBDRplus line-probe assay (LPA) on smear-positive sputum specimens with conventional culture and isoniazid (INH) plus rifampicin (RMP) drug susceptibility testing (DST).

DESIGN: Mycobacterium tuberculosis isolates tested at the Tanzanian Central TB Reference Laboratory (CTRL) were submitted for quality assurance of phenotypic DST to its supranational Quisinostat reference laboratory (SRL), together with ethanol-preserved sputum specimens for LPA DST.

RESULTS: Only 321 samples could be tested using LPA; of these, three were identified as being non-tuberculous mycobacteria using CTRL DST. Both tests had 269 sets with interpretable results. CTRL DST yielded almost the same number of interpretable results as LPA, with 90% concordance (kappa = 0.612, P < 0.001). Five (1.9%) multidrug-resistant (MDR) strains, 46 (17.1%) resistant to INH only and 0 RMP only, were found by CTRL DST. For the LPA, these results were respectively 5 (1.9%), 26 (9.7%) and 2 (0.7%).

This Could indicate that surface effects in ZnO/PMMA nanocomposite films have I dominant role over bulk effects for the SHG and THG processes (C) 2009 American Institute of Physics. [doi-10.1063/1.3253745]“
“Background-Activation of leukocytes with release of myeloperoxidase (MPO) has been linked to acute coronary disease. To date, studies investigating the diagnostic and prognostic performance of circulating MPO in patients with chest pain (CP) are mainly retrospective, of low size, and lack a cut-off value for MPO. Herein, we prospectively assess the

diagnostic and prognostic properties of MPO compared with sensitive troponin I (sTNI) in patients admitted to the emergency room with CP.

Methods and Results-One selleck inhibitor thousand, eight hundred and eighteen consecutive patients (mean age, 61.4 +/- 13.5 years; 33.6% female) admitted for CP underwent determination of MPO, sTnI, and B-natriuretic peptide plasma levels at admission and 3 hours and 6 hours thereafter. A cut-off for MPO Ion Channel Ligand Library was defined in 5000 population-based subjects. Baseline MPO levels were elevated in patients with acute myocardial infarction compared with patients with noncoronary CP. For all time-points accuracy of MPO was inferior to sTNI for predicting AMI. The sensitivity

of MPO to diagnose AMI at presentation was 73.5% compared with 90.7% for sTNI, and the specificity of MPO was 45.5% as opposed to 90.2%. B-natriuretic peptide levels also failed to demonstrate independent diagnostic information. Both MPO and B-natriuretic peptide were predictive for increased risk of adverse events at 30 days and 6 months, whereas their predictive value was weakened after covariate adjustment.

Conclusions-The data demonstrate that MPO and B-natriuretic peptide fail to provide incremental information for patients with acute onset CP when added to sensitive troponin. this website However, there is a potential value for both biomarkers as prognostic markers. (Circ Cardiovasc Genet. 2012;5:561-568.)”
“Aim:

Central venous access ports (CVAP) are often required to deliver chemotherapy to cancer patients. Arm-sited

CVAP are an alternative to traditional chest-sited CVAP, but their durability and complication rates have not been thoroughly compared.

Methods:

A retrospective analysis at a single institution was conducted of all patients who had a chest port inserted for chemotherapy over a 30-month period and compared to patients who had an arm port inserted over a subsequent 30-month period. The minimum follow-up period in patients who did not die from cancer was 6 months. The primary endpoint was successful use of the port, defined as a patient completing chemotherapy without a complication prompting removal of the port.

Results:

The success rate was not significantly different between arm port (92 patients) or chest port (49 patients) groups (88 vs 92%). There were no significant differences between infective or thrombotic complications in the two groups.

“
“P>Xyloglucan is the dominant hemicellulosic polysaccharide of the primary cell wall of dicotyledonous plants that plays a key role in plant development. It is well established that xyloglucan is assembled within Golgi stacks and transported in Golgi-derived vesicles to the cell wall. It is also known that the biosynthesis

of xyloglucan requires the action of glycosyltransferases including alpha-1,6-xylosyltransferase, beta-1,2-galactosyltransferase and alpha-1,2-fucosyltransferase activities responsible for the addition of xylose, galactose and fucose residues to the side chains. There is, however, a lack of knowledge CP-868596 order on how these enzymes are distributed within subcompartments of Golgi stacks. We have undertaken a study aiming at mapping these glycosyltransferases within Golgi stacks using immunogold-electron microscopy. To this end, we generated transgenic lines of tobacco (Nicotiana tabacum) BY-2 suspension-cultured cells expressing either the alpha-1,6-xylosyltransferase, AtXT1, the beta-1,2-galactosyltransferase, AtMUR3, or the alpha-1,2-fucosyltransferase AtFUT1 of Arabidopsis thaliana fused to green-fluorescent protein (GFP). Localization of the fusion proteins within the endomembrane system was assessed using confocal microscopy. Additionally,

tobacco cells were high pressure-frozen/freeze-substituted and subjected to quantitative immunogold labelling using anti-GFP antibodies Salubrinal molecular weight to determine the localization patterns of the GSK’872 nmr enzymes within subtypes of Golgi cisternae. The data demonstrate that: (i) all fusion proteins, AtXT1-GFP, AtMUR3-GFP and AtFUT1-GFP are specifically targeted to the Golgi apparatus; and (ii) AtXT1-GFP is mainly located in the cis and medial cisternae, AtMUR3-GFP is predominantly associated with medial cisternae and AtFUT1-GFP mostly detected over trans cisternae suggesting that initiation of xyloglucan side chains occurs in early Golgi compartments in tobacco cells.”
“Homozygosity for the methylenetetrahydrofolate reductase (MTHFR) 677C > T mutation (MTHFR TT) has been linked to an increased risk for stroke, coronary artery disease, and migraine headaches. The authors analyzed the potential

link between MTHFR 677C > T homozygosity and childhood stroke. A true association might facilitate screening, recurrence risk stratification, and treatment in patients with cerebrovascular disease. They performed a retrospective chart review of children tested for the MTHFR 677C >/T mutation; 533 patients underwent MTHFR testing, and 8% were homozygous for the MTHFR 677C > T mutation. There was no difference in the cohort compared with the prevalence in the general population. This suggests that the MTHFR 677 C > T polymorphism played a minimal role or no role in stroke risk. However, the data suggest that the MTHFR TT genotype may influence migraine susceptibility in children because there was a higher proportion of migraine patients (28.6%) with the MTHFR TT homozygous genotype.

The objective of this analysis was to assess longitudinal asthma status in 256 primary care patients in New York City enrolled in a trial to increase lifestyle physical activity. Methods. Patients were randomized to two protocols to increase physical activity during a period of 12 months. At enrollment, patients

completed the Asthma Quality of Life Questionnaire (AQLQ) and the Asthma Control Questionnaire (ACQ) and received asthma self-management instruction through an evaluative test and workbook. Exercise and self-management were reinforced every 2 months. The AQLQ was repeated every 4 months and the ACQ was repeated at 12 months. Results. The mean age was 43 years and 75% were women. At selleck screening library 12 months there were clinically important increases in physical activity with no differences between groups; thus, data were pooled for asthma analyses. The enrollment AQLQ score was 5.0 +/- 1.3 and increased to 5.9 +/- 1.1 corresponding to a clinically important difference. Correlations between AQLQ and physical activity were approximately 0.35 (p < .0001) at each time point. In a mixed effects model, the variables associated with improvement in AQLQ scores selleck products over time were male sex, less severe asthma, not taking asthma maintenance medications, fewer depressive

symptoms, and increased physical activity (all variables, p < .03). According to the ACQ, asthma was well controlled in 38% at enrollment and in 60% at 12 months (p < .0001). Conclusion. With attention to self-management, increased physical activity did not compromise asthma control and was associated with improved asthma.”
“Objectives: To determine the urologic health condition of spinal cord-injured (SCI) patients living in Turkey, and

to analyze the relationship between the prevalence of urologic health condition parameters and the patient’s characteristics.

Methods: click here Telephone call survey was conducted with a structured questionnaire among all members of Turkish Society of Spinal Cord Injured Patients.

Results: Data were obtained from 300 patients. Mean age was 42 years with a male/female ratio of 2.3, while the most common cause of injury was transport (35.3%). Although 70% were aware of potential kidney and bladder problems after injury >60% of the patients were not under regular urologic follow-up. Secondary health problems experienced as being most important was urination problems (50%). Of the patients 72.7% (83% in females vs 68% in males) had urinary incontinence (UI) during last 3 months, and 64.3% used clean intermittent catheterization (CIC) (68% in males vs 56% in females), while 73%, 57% and 26% of incontinent patients used diaper/pad, medication and condom catheter, respectively, and the use of CIC decreased with time. Surgical procedures on urinary tract were performed in 22.6% of the patients; stone surgeries were the most frequent ones.

Setting: Tertiary and university hospital.

Patients: Thirty patients with a history of ET dysfunction during pressure changes were examined.

Intervention: Minimally invasive LETP was performed with an 812-nm diode laser under local anesthesia as an outpatient procedure.

Main Outcome Measure: The ET function was tested pre-operatively and postoperatively by pressure chamber ET function test. Eustachian tube closing pressure (ETCP) was evaluated

as a measure of the tissue pressure of the ET. In cases of a severely impaired ET function, a “”blocked”" pattern was evident, and no measurement of ETCP was possible.

Results: Before minimally invasive LETP, 17 patients showed a completely blocked pattern. Postoperatively, 13 patients of this group showed CHIR-99021 purchase an improved ET function with a restored normal opening pattern (p < 0.001). The ETCP was reduced from 6.24 +/- 3.46 mbar preoperatively to 4.06 +/- 2.36 mbar postoperatively (p < 0.013).

Conclusion: The results strongly indicate that the effect of minimally invasive LETP can be proven by measuring the ET function in a pressure chamber. Results must be interpreted in combination with clinical

methods like Valsalva BMS-754807 purchase maneuver and tympanometry. Patients with ET dysfunction during pressure changes seem to benefit from the minimally invasive LETP.”
“Hydrothorax as a result of pleuroperitoneal communication (PPC) is an uncommon but a well-known GDC-0068 in vitro complication of continuous ambulatory peritoneal dialysis (CAPD). In this paper, we present a 60-year old man with diabetic renal failure who underwent CAPD. Two weeks after starting CAPD, chest radiographs showed a right-sided hydrothorax. Radioscintigraphy was performed and PPC was diagnosed. Eight

days after the diagnosis, thoracoscopic surgery was performed. The leakage points were closed by direct suturing with absorbable polyglycolic acid felt and fibrin glue. The patient resumed CAPD 2 weeks later, and there was no recurrence of the right hydrothorax. Video-assisted thoracic surgery with direct suturing represents a feasible method for treating PPC with confirmed fistulae.”
“The aim of this study was to examine chemical composition and biological activity of Gaultheria procumbens L essential oil (EO) against food spoilage and oral microorganisms. The components of EO were identified by GC-MS. Antimicrobial activity was determined against food spoilage (five bacteria and six fungal species) and oral microorganisms (eight bacteria and thirty two fungal species) by microdilution and microplate biofilm assay, antioxidant activity was tested using the persistent free radical 2,2-diphenyl-1-picryl hydrazyl (DPPH), while antiradical activity was examined by fluorescence spectroscopy and electron paramagnetic resonance spectroscopy (EPR). GC-MS analysis showed that methyl salicylate (96.90%) was the main component of the oil. Essential oil inhibited the growth of all microorganisms tested, i.e.