85 points (p = .002). The association persisted despite the adjustment for demographic and cardiovascular risk factors,

and after accounting for familial and genetic factors by comparing twins within pairs. A significant interaction was found between posttraumatic stress disorder (PTSD) and HRV, such that total power and ultra low frequency were associated Crenolanib with SRT in twins (n = 362) without PTSD, but not in those with PTSD. Conclusions: Lower frequency spectra of HRV are associated with verbal, but not visual, learning and memory, particularly in subjects without PTSD. This association may indicate that autonomic nervous system dysregulation plays a role in cognitive decline.”
“Objective: The objective of our study was to report our hospital and long-term results after reinterventions on the thoracic aorta.

Methods: Between 1986 and 2011, 224 reoperations on the proximal thoracic aorta after previous aortic surgery were performed in our institution. The number of reinterventions quadrupled during the course of the study period. Mean patient age was 58.1 years, and 174 patients

(77.7%) were male. An urgent/emergency operation was performed in 39 patients (17.4%). Indications for surgery included degenerative and chronic postdissection aneurysm (n = 166), false aneurysm (n = 31), active prosthetic infection (n = 16), acute dissection (n = 10), and other (n = 1). Surgical LCZ696 ic50 procedures involved the aortic root in 40.6% of patients, the ascending aorta in 9.4%, the aortic arch

in 24.6%, and the entire proximal thoracic aorta in 25.4%.

Results: Hospital mortality was 12.1%. On multivariate Prostatic acid phosphatase analysis, cardiopulmonary bypass time (odds ratio, 1.1023/minute; P < .001), and urgent/emergency status (odds ratio, 5.6; P < .001) emerged as independent predictors of hospital mortality. The follow-up was 98.7% complete. Estimated 1-, 5-, and 10-year survival rates were 84.4%, 72.5%, and 48.5%, respectively. Eighteen reinterventions were performed during follow-up-16 because of the progression of aortic disease at the proximal aorta (n = 2) and downstream aorta (n = 14). Freedom from reoperation at 1, 5, and 10 years was 95.6%, 90.2%, and 81.5%, respectively.

Conclusions: Reoperative aortic surgery was associated with satisfactory short-and long-term results, especially if carried out on an elective basis. The extent of the aortic replacement did not impact survival and was associated with a reduced need for reintervention. The progressive nature of aortic disease and the favorable results of elective primary aortic interventions suggest favoring aggressive aortic resections at initial surgery. (J Thorac Cardiovasc Surg 2013;S145:78-84)”
“Objective: Recent evidence suggests a role for diet quality in the common mental disorders depression and anxiety.