The structure was characterized as 24-methylene-3-oxocycloartane 13-carboxylic acid on the basis of NMR spectroscopic data.”
“This review sought to identify and summarize the instruments adapted or developed for measuring HRQoL among young children (< 8 years) living in resource-limited settings.
A review of the literature was conducted in two phases.
Phase one searched the PubMed, PsycInfo, Web of Knowledge (Web of Science), African Index Medicus, and SocINDEX databases and identified widely used child HRQoL instruments. Phase two reviewed the articles using the selected HRQoL instruments and extracted information on their SC79 mw use in resource-limited settings including adaption processes.
Seven instruments were identified that measured the HRQoL of young children. Six had been used in resource-limited settings. Of the 452 articles using these instruments, a total of 23 (5 %) studies used one AZD5153 solubility dmso of the identified HRQoL instruments in a resource-limited setting. Among these studies, 39 % employed an adaptation process for the use of that instrument. No instruments had been developed specifically for measuring the HRQoL of young children in resource-limited settings.
If pediatric HRQoL instruments are to be used in resource-limited settings, it is critical that they be developed and adequately adapted to those settings. Only then will interventions lead to larger increases in the overall
HRQoL and well-being of children.”
“Study Design. In vivo measurement of lumbar facet joint surface area.
Objective. To investigate lumbar facet joint surface area in relation to age and the presence of chronic low back pain.
Summary of Background Data. Facet joint surface area is Selleck CHIR99021 an important parameter for understanding facet joint function and pathology, but information on the lumbar facet joint is limited, especially in relation with age and low back pain symptoms.
Methods. In vivo measurements of the
lumbar facet joints (L3/L4-L5/S1) were performed on 90 volunteers ( 57 asymptomatic subjects and 33 chronic low back pain subjects) using subject-based 3-dimensional facet joint surface computed tomography models.
Results. The facet joint surface area increased significantly at each successive inferior level. In the low back pain subjects aged >40 years, both superior and inferior facet surface areas increased except superior facets at L5/S1 compared with younger subjects. In the asymptomatic subjects aged >40 years, only the superior facets showed an increase in the L3/4 facet surface area compared with younger subjects.
Conclusion. The lumbar facet areas measured in vivo in this study were similar to previous cadaveric studies. The lumbar facet area was significantly greater at the inferior lumbar levels and also increased with age. This age-related increase in the facet joint surface was observed more in the low back pain subjects compared with asymptomatic subjects.