The in line melt viscosity measurements showed that the flow behaviour of the starch system was influenced by the addition of either myristic or palmitic acids used. The examination of functional properties of the extrudates such as bulk density, water solubility index, expansion ratio, degree of gelatinization and water adsorptivity indicated that the addition of fatty acids affected the functionality

of starch systems. That is, the extrudate texture became more cohesive and compact whereas check details the water solubility exhibited by the system was decreased. Structural studies indicated that the crystallinity of starch-fatty acid extrudates was higher than that of the starch systems without fatty acid whereas all extrudates exhibited high glass transition temperatures and their structure was very rigid and brittle. (C) 2009 Elsevier Ltd. All rights reserved.”
“A specific micro-RNA (miRNA), microRNA 21 (miR-21), is strongly overexpressed in breast cancer cells. Antisense inhibition of miRNA function, an important VE-821 purchase tool for uncovering miRNA biology, which

is often used to knockdown miRNA, can cause a notable inhibition of cell growth. In this study, 5-fluorouracil (5-FU) was conjugated to polyamidoamine dendrimers via direct encapsulation; this method was then combined with antisense micro-RNA 21 (as-miR-21) strategies to evaluate 17-AAG supplier the effects of the growth suppression of breast cancer cells. Our results show that as-miR-21 strategies significantly improved the chemosensitivity of free 5-FU on breast cancer cells (MCF-7). In addition, not only could as-miR-21 effectively increase the apoptotic cell numbers but it could also bring down the migration ability of MCF-7 cells. Our results

provide invaluable information for the future design of drug-polymer complexes for multimodal cancer treatments. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 114: 3760-3766, 2009″
“The full clinical manifestations of complications due to odontogenic foci are rarely seen in daily dental practice and can take a clinically foudroyant course of development in young people owing to anatomic conditions, as demonstrated in this clinical case in a 12-year-old girl. Endodontic treatment of the first right upper molar was started owing to increasing toothache and swelling of fossa canina and the periorbital region. During the course of treatment, the patient exhibited an acute increase in orbital inflammation, which required immediate surgical intervention with postsurgical intravenous antibiotic administration. This case should serve to emphasize the crucial requirement for intensive attention to orbital symptoms after dental procedures.