Patients fulfilling the criteria, but suffering from other disorders were excluded. Results: Data of 20 patients were analyzed and 4 patients were excluded, as they had other associated conditions. Mean age at onset of symptoms was 2510 years; 12 (60) patients had narcolepsy with cataplexy, 4 (20) patients presented with all cardinal symptoms of narcolepsy, 8 (40) with 3 symptoms, while 8 (40) presented with 2 symptoms. History of Excessive Day-Time Sleepiness (EDS) was present in all patients. Three patients reported accidents due to sleep attacks, one being life-threatening. On PSG, mean sleep efficiency was 79.412.40.

Mean sleep latency during MSLT was 1.30 Target Selective Inhibitor Library minute (range: 0.30-2.30 minute) and mean REM latency was 2.580.64 minute. Conclusion: Narcolepsy

with and without cataplexy is infrequently seen in the North Indian population; however, clinical and polysomnographic features are similar to those observed in Western and other Asian populations.”
“Background: Noninvasive mechanical ventilation (NIMV) is an effective tool in treating patients with acute respiratory failure (ARF), since it reduces both the need for endotracheal intubation and the mortality in comparison with nonventilated patients. A particular issue is represented by the outcome of NIMV in patients referred to the emergency department for ARF and with a do-not-intubate (DNI) status because of advanced age or excessively critical conditions. Metabolism inhibitor This study evaluated long-term survival in a group of elderly patients with acute hypercapnic ARF who had a DNI order and who were successfully treated by NIMV.\n\nMethods: The population consisted of 54 patients with a favorable outcome after NIMV for ARF. They were followed up for 3 years by regular control visits, with at least one visit every 4 months, or as needed according to the patient’s GSK J4 condition. Of these,

31 continued NIMV at home and 23 were on long-term oxygen therapy (LTOT) alone.\n\nResults: A total of 16 of the 52 patients had not survived at the 1-year follow-up, and another eight patients died during the 3-year observation, with an overall mortality rate of 30.8% after 1 year and 46.2% after 3 years. Comparing patients who continued NIMV at home with those who were on LTOT alone, 9 of the 29 patients on home NIMV died (6 after 1 year and 3 after 3 years) and 15 of the 23 patients on LTOT alone died (10 after 1 year and 5 after 3 years).\n\nConclusion: These results show that elderly patients with ARF successfully treated by NIMV following a DNI order have a satisfactory long-term survival.”
“This paper presents a study of the evolution of the Raman backscattered intensity used to follow the modifications of polymer microstructure in real time during a tensile test.