7 The transition period early after hospital discharge represents

7 The transition period early after hospital discharge represents a window of opportunity to positively influence patient outcomes using targeted interventions.8 While timely care by healthcare Pacritinib mechanism professionals may be an important component

of transitional care interventions,9 the optimal strategies to reduce readmissions or improve survival among patients with HF are unknown. Adding to the complexity of HF management is multimorbidity,10 which makes the care of patients, and implementation of effective interventions and programmes more challenging. Evidence from systematic reviews

suggests that quality improvement (QI) strategies such as multidisciplinary outpatient disease management programmes are beneficial for reducing mortality, and all-cause and HF-specific hospital admissions.5 Most of these QI strategies are complex (ie, multifaceted with multiple targets and components). However, few studies have described such interventions and their components in sufficient detail to allow for in-depth and clinically meaningful comparison(s), and it is unknown which components (delivered by whom and to which targets) contribute to their impact. Furthermore, little is known about which QI interventions exist for early events after discharge for inpatients, and no systematic review has previously investigated the impact of QI interventions

that focus specifically on optimising the transition of patients with HF from the hospital to independent living. The objectives of our study are to conduct a scoping review of the literature for randomised controlled trials (RCTs) and systematic reviews to determine which QI strategies aimed at transitioning adult patients with HF from the hospital back into independent living are effective for reducing hospital readmissions and mortality. We will also investigate the specific components of QI interventions to identify Cilengitide common elements of those that are effective, and to specifically determine elements that contribute to their effectiveness. Methods and analysis We will use the scoping review methodology as outlined by Arksey and O’Malley11 to conduct our study, which is currently considered the most rigorous methodology for conducting scoping reviews. Our protocol was conceived, developed and reviewed by all members of our team.

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